PROSPECTIVE STUDY EVALUATING INCOBOTULINUMTOXINA FOR CERVICAL DYSTONIA OR BLEPHAROSPASM: INTERIM RESULTS FROM THE FIRST 145 SUBJECTS WITH CERVICAL DYSTONIA

Prospective Study Evaluating IncobotulinumtoxinA for Cervical Dystonia or Blepharospasm: Interim Results from the First 145 Subjects with Cervical Dystonia

Background: We report the interim results from XCiDaBLE: A large prospective, observational "naturalistic" study evaluating Xeomin® (incobotulinumtoxinA) for cervical dystonia or blepharospasm in the United States.Methods: Subjects with CD are followed for 2 treatment cycles and monitored via Interactive Voice/Web Response.Subject-reported scal

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Clinical and genomic characterization of chemoradiation-resistant HPV-positive oropharyngeal squamous cell carcinoma

IntroductionMost patients with HPV-positive oropharyngeal squamous cell carcinoma (OPSCC) have an excellent response to chemoradiation, and trials are now investigating de-escalated treatment.However, up to 25% of patients with HPV-positive OPSCC will experience recurrence, and up to 5% will even progress through primary treatment.Currently, there

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Temperature and medium structurization effect on spontaneous evolution of domains and bubbles in magnetic nanostructures

Spontaneous evolutions of domains in magnetic nanowires and of magnetic bubbles in open ferromagnetic nanolayers are investigated using micromagnetic simulations.We compare temperature dependent dynamics of domain wall (DW) systems in Permalloy (Py) nanowires and systems of chiral DWs in ultra-thin nanowires with perpendicular magnetic anisotropy (

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